Business Type:Manufacturer
Country/Region:China
Ddu Verified
HOT Rank
8/10
Taizhou Crene Biotechnology Co.,Ltd.
We are professional supplier of API and intermediates.
Business Type:Manufacturer
Country/Region:China
Ddu Verified
HOT Rank
8/10
D-cloprostenol sodium (15 g per head) is the lowest dose that consistently achieves abortion; D-cloprostenol causes mild adverse effects including salivation, defecation and hyperventilation in bitches weighing less than 10 kg. Intra-vesicle administration of a single low dose of d-cloprostenol is a safe and successful technique to induce abortion in the bitch[1].
D-Cloprostenol sodium and PGF2 alpha are equipotent, about 150 times more potent than dl-cloprostenol (P < 0.05) and approximately 280 times more potent than PGE1 in inhibiting [3H]PGF2 alpha binding to corpus luteum cell membranes. However, d-cloprostenol and PGF2 alpha are about 10 times more potent than dl-cloprostenol and approximately 95 times more potent than PGE1 in myometrial cell membranes[2].